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Does spironolactone make breasts bigger? Spironolactone frequently causes breast pain and breast enlargement in women. This is "probably because of estrogenic effects on target tissue." As with breast enlargement caused by spironolactone in women, gynecomastia due to spironolactone in men is often although inconsistently accompanied by breast tenderness. What can damage the kidneys? Consuming large quantities of salt: Diets high in sodium increase blood pressure levels. High blood pressure damages the kidneys over time, and is a leading cause of kidney failure. What is the generic for Aldactone? Aldactone (spironolactone) is classified as a potassium-sparing diuretic. It is prescribed for the treatment of congestive heart failure, cirrhosis of the liver, and kidney disease. It can also be used in combination with other drugs to treat diuretic induced low potassium and high blood pressure.
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