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What is the main difference between schizophrenia and schizoaffective disorder? If you have schizoaffective disorder, you have one or more of the following symptoms: Depression: Sadness and feelings of hopelessness, helplessness and/or worthlessness. Mania: Racing thoughts, grandiose beliefs, sleeplessness and/or risky behaviors. Hypomania: The symptoms are similar to mania but less intense. Why do people with schizophrenia stop taking their meds? People with schizophrenia may stop taking their medication because it can have side-effects, some of which can be unpleasant. Some people with schizophrenia begin feeling better and conclude that they no longer need to take their medication, but then become much more likely to have their symptoms reoccur.
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